![]() A study published in the journal PAIN is the first to show how morphine interacts with toll-like receptor 4 to contribute to pain evolution and bone loss. On the left, cells isolated from breast cancer cells were treated with RANKL, a growth factor that stimulates bone resorption, to produce osteoclasts (pink). Most commonly used in pain …A study published in the journal PAIN is the first to show how morphine interacts with toll-like receptor 4 to contribute to pain evolution and bone loss. ![]() Go to: Indications FDA-approved usage of morphine sulfate includes moderate to severe pain that may be acute or chronic. Dhingra, MD Fact checked by Marley Hall Many people wonder about the uses, forms, and side effects of morphine, especially since morphine sulfate is perhaps the most misunderstood and the most feared of all the medications used to treat pain.
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